Simon Yung Wa Sin

Simon Yung Wa Sin

Postdoctoral Fellow
Simon Yung Wa Sin

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Education

Simon Yung Wa Sin is a postdoctoral fellow in the Department of Organismic & Evolutionary Biology at Harvard University. He obtained a BSc degree in Biology with first class honours at the Chinese University of Hong Kong (CUHK) in 2005, and an MPhil degree in Biology at CUHK in 2008. He was awarded a Croucher Scholarship and joined the Wildlife Conservation Research Unit in the Zoology Department at the University of Oxford, where he accomplished his DPhil study in 2013. 

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Research Interests

Simon Sin’s research is inter-disciplinary and aims to understand how genetics affects phenotypic traits and behaviours. His research interests span the fields of molecular ecology, evolutionary biology and behavioural genomics. His studies include mate choice, host-parasite/microbiome co-evolution, phylogenomics, and gene family evolution. Simon is currently conducting research on behavioural genomics of the Leach's storm petrel, and on evolutionary genomics of several other avian species to investigate mate choice, speciation, introgression and genotype-phenotype association.

 

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Publications

P Grayson, SYW Sin, T Sackton, SV Edwards (2017) Comparative genomics as a foundation for evo-devo studies in birds. In Avian and Reptilian Developmental Biology (pp. 11-46). Humana Press, New York, NY.

YW Sin, C Newman, HL Dugdale, C Buesching, M-E Mannarelli, G Annavi, T Burke, DW Macdonald (2016) No compensatory relationship between the innate and adaptive immune system in wild-living European badgers. PLoS One 11(10): e0163773. doi:10.1371/journal.pone.0163773

CD Buesching, HV Tinnesand, YW Sin, F Rosell, T Burke, DW Macdonald (2016) Coding of Group Odor in the Subcaudal Gland Secretion of the European Badger Meles meles: Chemical Composition and Pouch Microbiota. In Chemical Signals in Vertebrates 13 (pp. 45-62). Springer International Publishing.

YW Sin, G Annavi, C Newman, C Buesching, T Burke, DW Macdonald, HL Dugdale (2015). MHC class II assortative mate choice in European badgers (Meles meles). Molecular Ecology. 24(12): 3138–3150. doi: 10.1111/mec.13217

N Kenny, YW Sin, A Hayward, J Paps, KH Chu, JHL Hui (2015) The phylogenetic utility and functional constraint of microRNA flanking sequences. Proceedings of the Royal Society B 282: 20142983. doi: 10.1098/rspb.2014.2983

G Annavi, C Newman, HL Dugdale, CD Buesching, YW Sin, T Burke & DW Macdonald (2014) Neighbouring-group composition and within-group relatedness drive extra-group paternity rate in the European badger (Meles meles). Journal of Evolutionary Biology 27(10): 2191–2203. doi: 10.1111/jeb.12473

YW Sin, G Annavi, HL Dugdale, C Newman, T Burke & DW Macdonald (2014) Pathogen burden, co-infection and major histocompatibility complex variability in the European badger (Meles meles). Molecular Ecology 23(20): 5072–5088. doi: 10.1111/mec.12917

YW Sin, NJ Kenny, Z Qu, KW Chan, KWS Chan, SPS Cheong, RWT Leung, TF Chan, WG Bendena, KH Chu, SS Tobe, JHL Hui (2014) Identification of putative ecdysteroid and juvenile hormone pathway genes in the shrimp Neocaridina denticulata. General and Comparative Endocrinology. 214: 167–176. doi: 10.1016/j.ygcen.2014.07.018

NJ Kenny*, YW Sin*, X Shen, Q Zhe, W Wang, TF Chan, SS Tobe, SM Shimeld, KH Chu & J Hui (2014) Genomic sequence and experimental tractability of a new decapod shrimp model, Neocaridina denticulata. Marine drugs 12(3), 1419−1437. (*Equal contribution)

K Bilham, YW Sin, C Newman, CD Buesching & DW Macdonald (2013) An example of life history antecendence in the European badger (Meles meles): rapid development of juvenile antioxidant capacity, from plasma vit-E analogue. Ethology Ecology & Evolution. doi:10.1080/03949370.2013.767861

YW Sin, H Dugdale, C Newman, DW Macdonald & T Burke (2012) Evolution of MHC class I genes in the European badger (Meles meles). Ecology and Evolution 2(7): 1644−1662. doi: 10.1002/ece3.285

YW Sin, CD Buesching, T Burke & DW Macdonald (2012) Molecular characterization of the microbial communities in the subcaudal gland secretion of the European badger (Meles meles). FEMS Microbiology Ecology 81(3): 648–659. doi: 10.1111/j.1574-6941.2012.01396.x

YW Sin, H Dugdale, C Newman, DW Macdonald & T Burke (2012) MHC class II genes in the European badger (Meles meles): characterization, patterns of variation, and transcription analysis. Immunogenetics 64(4): 313−327. doi: 10.1007/s00251-011-0578-9

R Lizundia, C Newman, CD Buesching, D Ngugi, D Blake, YW Sin, DW Macdonald, A Wilson & D McKeever (2011) Evidence for a Role of the Host-specific Flea (Paraceras melis) in the Transmission of Trypanosoma (Megatrypanum) pestanai to the European Badger. PLoS ONE 6(2): e16977. doi:10.1371/journal.pone.0016977

YW Sin, KH Chu & C Yau (2009) Isolation and characterization of highly polymorphic microsatellites in the mitre squid, Uroteuthis (Photololigo) chinensis. Molecular Ecology Resources 9: 1460−1559

YW Sin, JCY Lai, PKL Ng & KH Chu (2009) Phylogeny of Dorippoidea (Crustacea: Decapoda: Brachyura) inferred from three mitochondrial genes. Invertebrate Systematics 23: 223-230

YW Sin, C Yau & KH Chu (2009) Morphological and genetic differentiation of two loliginid squid, Uroteuthis (Photololigo) chinensis and U. (P.) edulis (Cephalopoda: Loliginidae), in Asia. Journal of Experimental Marine Biology and Ecology 369: 22−30

M Mitsuhashi, YW Sin, HC Lei, TY Chan & KH Chu (2007) Systematic status of the caridean shrimp families Gnathophyllidae Dana and Hymenoceridae Ortmann (Crustacea, Decapoda, Caridea): A preliminary examination based on nuclear rDNA sequences. Invertebrate Systematics 21: 613−622

YW Sin, KH Chu, PKL Ng (2006) Mitochondrial DNA Phylogeny of the family Dorippidae (Decapoda, brachyura). Integrative and Comparative Biology 46(S1): E131

Contact Information

Department of Organismic and Evolutionary Biology
Museum of Comparative Zoology
Harvard University
26 Oxford Street
Cambridge, MA 02138
p: 617-496-8398

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